HANOVER, N.H. — Quinnipiac launched four home runs to ruin Dartmouth’s home opener on Wednesday afternoon, knocking off the Big Green at Red Rolfe Field at Biondi Park, 11-5. Vincent Guglietti was a perfect 4-for-4 at the plate with one of those long balls while scoring three runs and driving in two to lead the Bobcats (6-15).

Senior Dustin Selzer went 3-for-5 with a pair of RBIs as well to pace the Dartmouth (4-13) offense, and sophomore Nick Ruppert hit a solo blast for his first career homer.

Quinnipiac entered the game with just one home run in its first 20 games, but muscled up to subdue the Big Green. Two of the four Bobcat round-trippers came with no one on base, but Ryan Nelson and Scott Donaghue each hit three-run shots to drain the energy from the Dartmouth faithful and allow Quinnipiac to hand the Big Green just their second home non-conference loss in the past six seasons.

The two teams traded runs in the first as Guglietti delivered a two-out RBI single between first and second in the top half, and Selzer yanked a ball down the third-base line for a double to plate senior Jeff Keller who had singled and stolen second.

On the very first pitch of the second inning, Nic Civale sent an offering from sophomore Adam Charnin-Aker over the fence in left for his first home run of the year. Nelson popped this three-run bomb in the fourth after Guglietti and Donaghue had singled for a 5-1 Bobcat lead.

Dartmouth rallied in the bottom of the fifth against Quinnipiac starter Matthew Lorenzetti, beginning with Ruppert’s four-bagger into the left-field netting with one down. Junior Matt Parisi followed with a base hit but was thrown out at the plate attempting to score on Keller’s screaming liner to left for a double. When Selzer followed with an RBI single, Lorenzetti was replaced on the mound by Nick Fabrizio, who was greeted by junior Thomas Roulis with a triple into the right-field corner to make it a 5-4 game. After a walk put runners on the corners, junior Nick Lombardi hit a liner to right that hung up just long enough for Mike Blumenthal to make a diving catch and keep the tying run from scoring.

The Bobcats got two of those runs back against the Big Green bullpen in the very next frame as Blumenthal poked a single through the right side to score Donaghue from third and Brian Ruditys lofted a sacrifice fly to score Nelson who had doubled.

Guglietti put Quinnipiac up 8-4 in the seventh with a solo homer to right, and Donaghue sent his three-run blast onto Park Street beyond left field with two gone in the ninth for the final Bobcat runs.

In the bottom of the ninth, Dartmouth managed to push one run across the plate, but Gary Binkiewicz got the final out on a grounder to third to close out the game.

Fabrizio (1-1) picked up the victory with 1.1 scoreless innings of relief of Lorenzetti, who surrendered four runs on eight hits in 4.2 innings. Left-hander Matthew Osieja was perfect in the seventh and eighth stanzas to allow Quinnipiac to build up its lead.

Taking the loss was Charnin-Aker (0-2) as he yielded five runs on seven hits over 4.1 innings of work to go along with five strikeouts and no walks. Freshman Chris Burkholder was the most effective of three Big Green relievers, giving up one run on two hits over 2.2 frames.

Each of the top five hitters in the Dartmouth lineup — Ruppert, Parisi, Keller, Selzer and Roulis — had at least two hits. But the bottom four spots managed just one knock, a double by junior Matt MacDowell.

Dartmouth returns to Red Rolfe Field at Biondi Park this weekend for a pair of Ivy League doubleheaders. The Big Green (1-3 Ivy) will host Columbia (8-14, 2-2 Ivy) on Saturday at noon, then Penn (11-10, 4-0 Ivy) on Sunday at noon as well.

Notes: Since Red Rolfe Field was renovated before the 2009 season to include Biondi Park, Dartmouth is now 67-11 (.859) and 23-2 (.920) against non-conference opponents at the facility … the Big Green had beaten Quinnipiac in the previous seven meetings and hold a 10-6 lead in the all-time series … Keller has nine doubles in 17 games after leading all Division I players in doubles per game last season.