The Big Green suffered their seventh straight loss to start the 2016-17 season and ninth straight against the Catamounts.
Dartmouth has won 57 of 100 games against Vermont throughout the years, but the Catamounts have won eight straight and 16 of the last 17.
Boston College hit 11 of its first 17 three-point attempts and led by as many as 23 the Big Green suffered their sixth straight loss to open the season.
Dartmouth renews its series with the Eagles at the Conte Forum on Saturday afternoon as the two teams meet for the first time in four years.
Dartmouth held Old Dominion to three field goals for the first 17 minutes of the second half and 28.8 percent shooting for the game, but the Monarchs fought off the Big Green down the stretch.
The only time the Big Green have ever played the Monarchs came in December of 1976 when Old Dominion downed Dartmouth, 95-70.
Guilien Smith and Evan Boudreaux each had 21 points for the Big Green, but the host Lancers drained 12 three-pointers and fought off Dartmouth down the stretch.
Dartmouth plays its first of four straight games on the road when it takes on Longwood for on Monday night in Farmville, Virginia.
Miles Wright scored all 16 of his points in the second half as Dartmouth hit 11 three-pointers in the game, but the Red Foxes shot almost 60 percent in the second half to hold off the Big Green.
The men's basketball team hosts Marist in the second game of a doubleheader with the women at Leede Arena.
The men's and women's basketball teams will host a free youth clinic at Leede Arena on Nov. 25 from 2:00-3:30.
Taylor Johnson had 11 points and three assists while Evan Boudreaux supplied a team-high 18 points, but Tyler Nelson had a career-high 28 for the visiting Stags.