Dartmouth fell behind by 23 in the first half, and even a 16-0 run spanning the two halves couldn't bring the Green all the way back at Princeton on Saturday night.
The host Quakers outscored Dartmouth 17-5 over the final five minutes to send the Big Green to their third straight defeat.
Dartmouth looks to end a two-game skid at venues where it has won a total of nine games in the last 56 seasons.
Cornell scored 16 of the final 19 points of the game to rally for a 77-73 triumph at Leede Arena on the night that senior Connor Boehm surpassed 1,000 career points.
Columbia started the game with a 10-point run then added a 16-point stretch later in the first half to lead from wire to wire and hand the Big Green a 17-point loss.
Dartmouth will try to finish off a perfect homestand of at least five games for the first time since the 1958-59 season with the Lions and Big Red in town this weekend.
Evan Boudreaux scored 18 points and hauled in 13 rebounds to record his fifth double-double to help him earn his sixth Ivy rookie weekly honor.
Malik Gill and Taylor Johnson scored all of their combined 21 points in the second half to help Dartmouth rally from an 11-point deficit to knock off the five-time defending Ivy champs.
Dartmouth looks to avenge its seven-point loss against the Crimson back on Jan. 9 when Harvard comes to Leede Arena for a 7 p.m. tip.
Six players scored in double figures, including Wesley Dickinson with 14 on 6-of-6 shooting, as Dartmouth hammered visiting Pine Manor on Saturday, 121-56.
Dartmouth will host second-year program Pine Manor for its final non-conference tune up before the Ivy League schedule gets going in earnest.
The Big Green straddled the two halves by putting together an 18-2 run and shot a season-high 53.5 percent to avenge last year's CIT loss to the Golden Griffins.